Mitochondria are known as the “powerhouses” of the cell, but their role in reproduction goes far beyond energy production. Especially in egg cells, they are not just important—they are decisive. Without healthy and functional mitochondria, an egg cell cannot mature properly, be fertilized successfully, or support embryonic development in its earliest stages.

What do mitochondria do in the egg cell?

The egg cell is the largest and one of the most metabolically active cells in the human body. It contains between 100,000 and 600,000 mitochondria—many times more than any other cell type. The reason is simple: in the first days after fertilization, before the embryo begins to express its own genes, all energy-dependent processes rely entirely on the mitochondrial function of the egg cell.

Mitochondria produce adenosine triphosphate (ATP)—the cell’s energy currency—through the process of oxidative phosphorylation. ATP is absolutely essential for:

• egg cell maturation (meiotic division),

• formation of correct and symmetrical spindle structures (crucial for genetic stability),

• fertilization by the sperm cell,

• embryonic cell divisions (cleavage),

• and successful implantation in the uterine lining.

What happens when mitochondria do not function properly?

With increasing age (especially after 35), levels of mitochondrial DNA (mtDNA) decline, mitophagy becomes impaired, oxidative stress increases, and egg quality drops sharply. This is associated with:

• a higher risk of chromosomal abnormalities (aneuploidy),

• failed fertilization,

• arrested embryonic development,

• and a lower chance of implantation.

That is why mitochondria are not just one of many factors—they are the foundation of successful reproduction.

How Fundamentals by Mitopia supports mitochondrial function and reproductive potential

Our formula contains Urolithin A (1000 mg), PQQ (60 mg), and CoQ10 (200 mg)—three compounds with direct, synergistic effects on mitochondrial health. They are encapsulated in a liposomal delivery system that provides approximately 50% absorption, making the dosage not only high, but truly effective. The ingredients are precisely calibrated to this bioavailability to achieve real physiological impact.

Here is how the active ingredients work:

• Urolithin A – activates mitophagy, the process of removing damaged mitochondria and regenerating new, healthy ones. This helps “rejuvenate” the mitochondrial network in egg cells.

• PQQ (pyrroloquinoline quinone) – stimulates mitochondrial biogenesis (the creation of new mitochondria), increasing both their number and functionality.

• CoQ10 (ubiquinone) – participates in the mitochondrial electron transport chain, improving ATP production and protecting the mitochondrial membrane from oxidative stress.

Cellular energy = fertile potential

Maintaining healthy mitochondrial function in egg cells is not merely a good practice—it is a strategy for higher fertility and healthier embryos. Scientists increasingly view mitochondrial quality as a key predictor of success in in vitro fertilization (IVF), including the implantation potential of blastocysts.

With Fundamentals by Mitopia, we support life from its very cellular beginning.